Perioperative Neurocognitive Disorders
Conditions
Interventions
Non-oral frailty group:None
Sponsors
The First Hospital of Shanxi Medical University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 65 years old; 2. ASA classification: Grade II - III; 3. Body Mass Index (BMI): between 18.5 - 28 kg/m^2; 4. Clear consciousness, able to complete the scale assessment independently or under the guidance of researchers; 5. The patient agrees to sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Pre-existing physical dysfunction (language, hearing, or visual impairment) before admission 2. Severe neuropsychiatric disorders (hysteria, dementia) and craniocerebral injury 3. Severe hepatic or renal disease 4. Long-term use of steroid hormones (oral, intramuscular, or intravenous) and probiotics or other microecological preparations
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive rate of postoperative cognitive dysfunction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitive dysfunction score;3-minute Diagnostic Interview for CAM?defined Delirium(3D-CAM);Oral Frailty Score;Richards-Campbell Sleep Questionnaire;Length of stay;The dosage of postoperative analgesic drugs; | — |
Countries
China
Contacts
Public ContactLv Jieping
The First Hospital of Shanxi Medical University
Outcome results
None listed