Spinal deformity
Conditions
Interventions
Spinal deformity group:None
Control group:None
Sponsors
Department of Orthopedic Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
8 Years to 50 Years
Inclusion criteria
Inclusion criteria: Cohort of patients with spinal deformities: 1. No gender restrictions 2. Age 8 - 50 years old 3. Clinically diagnosed with one of the following: • Juvenile Idiopathic Scoliosis (AIS) • Adult Spinal Deformity (ASD, including degenerative/idiopathic adult scoliosis, etc.) • Congenital Spinal Deformity (such as hemivertebra, segmentation disorder, etc.) • Syndromic Spinal Deformity (such as NF1, Marfan, etc., based on clinical or genetic diagnosis) 4. Able to cooperate and complete at least standardized 3D surface scans of the back/trunk and questionnaire collection; two-dimensional clinical general radiographs and facial/mastoid-related collection are implemented according to modular consent, and subjects can choose to exit specific photography modules without affecting the rest of the research process 5. Able to cooperate and complete standardized 3D surface scans, 2D clinical general radiographs, and questionnaire collection 6. Agree to the de-identification storage and analysis of research data and sign the informed consent form 7. Have conventional clinical imaging data (such as full spine X-rays, CT, etc.) that can be used for research purposes 8. If undergoing spinal deformity correction surgery, promise to participate in all planned follow-ups Control group subjects (healthy subjects/non-spinal deformity population) 1. Age 8 - 50 years old 2. No clinical history of definite spinal deformity, no known moderate to severe trunk asymmetry signs 3. Able to cooperate and complete at least standardized 3D surface scans of the back/trunk and questionnaire collection; two-dimensional clinical general radiographs and facial/mastoid-related collection are implemented according to modular consent, and subjects can choose to exit specific photography modules without affecting the rest of the research process 4. Agree to the de-identification storage and analysis of research data and sign the informed consent form. Note: To address the module participation differences due to privacy concerns (such as female subjects' selective withdrawal from facial/mastoid collection), the study will systematically assess potential selection bias: compare the differences in baseline characteristics such as gender, age, BMI, curvature and severity between "completed vs. uncompleted" specific module collections, and conduct sensitivity analysis using multiple imputation or inverse probability weighting when necessary to evaluate the impact of this bias on the main conclusions.
Exclusion criteria
Exclusion criteria: 1. Unable to safely or stably maintain the standardized standing position to complete the collection (such as severe vertigo, inability to stand, severe neurological dysfunction resulting in a significant risk of falling); 2. There are unavoidable obstructions or severe skin problems in the key collection area that lead to collection failure (large dressings, severe skin lesions/infections, etc.; those who can be postponed for re-collection are not considered excluded); 3. Previous history of trunk surgeries other than spinal deformity correction surgery, such as those involving the breasts, chest, abdomen, lower back, and both lower limbs; 4. Clearly refuse any form of photography/3D collection (if only refusing collection of the breasts or face, it can be regarded as module exit rather than overall exclusion); 5. The researcher determines that there is significant psychological discomfort or other reasons that make it inappropriate to participate in appearance-related collection; 6. Unable to complete follow-up; 7. Suffering from severe systemic diseases or mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| reliability;validity; | — |
Secondary
| Measure | Time frame |
|---|---|
| responsiveness/interpretability; | — |
Countries
China
Contacts
Public ContactShengru Wang
Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences
Outcome results
None listed