Ischaemic heart disease
Conditions
Interventions
13N-Ammonia PET:None
Sponsors
The First Affiliated Hospital of the Air Force Medical University of the People's Liberation Army of China
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with suspected or confirmed ischaemic heart disease who require myocardial perfusion imaging and/or coronary flow reserve (CFR) assessment; 2. Patients who voluntarily agree to undergo 13N-ammonia PET/CT or PET/MR scanning, have signed an informed consent form, demonstrate good compliance, and are able to cooperate fully with the examination and follow-up.
Exclusion criteria
Exclusion criteria: 1. Unstable angina, acute coronary syndrome, or within 2 to 4 days following an acute myocardial infarction; 2. Sick sinus syndrome or symptomatic bradycardia, without an active pacemaker; 3. Second- or third-degree atrioventricular block without a functional pacemaker; 4. Systolic blood pressure below 90 mmHg. The risk associated with severe hypotension is higher in patients with autonomic dysfunction, hypovolaemia, stenosis of the left main coronary artery, valvular heart disease with stenosis, pericarditis, pericardial effusion, or carotid artery stenosis associated with cerebrovascular insufficiency; 5. Uncontrolled hypertension (systolic blood pressure >200 mmHg or diastolic blood pressure >110 mmHg); 6. Patients with persistent wheezing and bronchospastic lung disease, or those with a history of significant reactive airway disease, should not undergo an adenosine stress test; 7. Known hypersensitivity to adenosine; 8. Pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Baseline MBF in each myocardial segment;Maximum blood flow (MBF) in each segment of the myocardium;CFR values for each myocardial segment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Check operation time; | — |
Countries
China
Contacts
Public ContactXiang Li
The First Affiliated Hospital of the Air Force Medical University of the People's Liberation Army of China
Outcome results
None listed