Improve difficult extubation of mechanical ventilation
Conditions
Interventions
Control group:Routine ICU treatment for mechanical ventilation plus sham TEAS intervention.
Intervention group:Receive routine mechanical ventilation treatment in the ICU combined with standardized TEAS intervention.
Sponsors
Jiangsu Provincial Hospital of Integrated Traditional Chinese and Western Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 80 years old; 2. Received invasive mechanical ventilation for no less than 48 hours in the ICU, with an expected duration of subsequent mechanical ventilation >= 24 hours and a risk of difficult extubation; 3. Relatively stable hemodynamics, without continuous vasopressor dependence or with only low-dose vasopressors; 4. Stable control of underlying diseases; no acute exacerbation of chronic obstructive pulmonary disease, chronic cardiac insufficiency, sequelae of cerebrovascular diseases, diabetes and other chronic conditions; 5. Written informed consent obtained from the patients or their legal representatives.
Exclusion criteria
Exclusion criteria: 1. Patients with unplanned extubation or requirement for re-intubation (including intubation for surgical/medical reasons and extubation upon family request for treatment withdrawal); 2. Patients with a history of epilepsy or diseases that may induce epilepsy, such as severe cerebral hemorrhage, craniocerebral trauma, intracranial tumor and intracranial infection; 3. Patients unable to be weaned from ventilation or extubated due to irreversible brain injury; 4. Patients with implanted cardiac pacemakers; 5. Patients with skin allergy or skin damage; 6. Pregnant or lactating women; 7. Patients participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Extubation success rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cough decibels;Diaphragmatic excursion variability;Peak cough flow;Incidence of mechanical ventilation?related complications;Duration of mechanical ventilation;Total length of hospital stay;ICU length of stay;ICU mortality;In?hospital mortality;28?day mortality; | — |
Countries
China
Contacts
Public ContactXiaofei Huang
Jiangsu Provincial Hospital of Integrated Traditional Chinese and Western Medicine
Outcome results
None listed