Stroke: sudden onset of contralateral limb numbness, weakness, sensory deficits, monocular vision loss, vertigo, diplopia, bilateral vision loss, ataxia, etc.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for ischemic stroke as defined by the "Chinese Guidelines for the Diagnosis of Major Cerebrovascular Diseases 2019", confirmed by cranial CT or MRI. 2. Aged 18 to 65 years, any gender. 3. First-ever stroke, with a disease duration of 1 to 6 months. 4. Unilateral hemiplegia, with Brunnstrom stage >= III. 5. No significant aphasia or cognitive impairment (MMSE >= 24). 6. No progression of neurological symptoms for more than 48 hours. 7. Signed informed consent form. 8. Ability to comply with all study procedures and participate in all treatments and assessments.
Exclusion criteria
Exclusion criteria: 1. Severe depression; 2. Comorbid with other severe neurological or psychiatric disorders (including but not limited to dementia, Parkinson's disease, or alcoholism); 3. Comorbid with severe medical conditions that persistently affect the patient's full participation in the study (including but not limited to advanced chronic obstructive pulmonary disease, hepatic or renal failure, advanced congestive heart failure, severe anemia, coagulation disorders, malignant tumors, etc.), with an expected survival of less than 6 months; 4. Comorbid with other diseases affecting the function of the affected limb (including but not limited to severe arthritis, Dupuytren's contracture, etc.); 5. Concurrent participation in another investigational therapeutic or interventional study, or participation in other similar clinical trials within the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment for Motor Function (FMA) Score;24-hour Heart Rate;128-channel Electroencephalography (128-channel EEG); | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh Sleep Quality Index (PSQI);Modified Barthel Index (MBI);Fugl-Meyer Balance Scale (FMA-Balance) Score;Muscle Tone;Body Temperature; | — |
Countries
China
Contacts
Beijing Bo'ai Hospital