IgA nephropathy
Conditions
Interventions
Group1:High-quality protein diet Chitosan oligosaccharides
Group2: High-quality protein diet
Group3: Normal diet Chitosan oligosaccharides
Group4: Normal diet
Sponsors
Minhang District Central Hospital, Shanghai
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-70 years, diagnosed with IgA nephropathy confirmed by renal biopsy, with no previous treatment with glucocorticoids, immunosuppressants, or kidney transplantation, 24-hour urinary protein quantification 0.5-3.5 g, eGFR >= 30 mL/min/1.73 m^2. 2. Stable use of RAS inhibitors (ACEI/ARB). 3. Participants and their families agree to join the clinical study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Individuals with AIDS or HIV infection, malignant tumors, or who have undergone bone marrow transplantation; 2. Those undergoing immunosuppressive therapy, including immunosuppressants, cancer chemotherapy, or treatment to prevent organ transplant rejection; 3. Excluding cases with co-infections, tumors, pregnancy, and other conditions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Estimated glomerular filtration rate decreased;Blood creatinine; | — |
Countries
China
Contacts
Public ContactHe Haidong
Minhang District Central Hospital, Shanghai
Outcome results
None listed