Postoperative nausea and vomiting (PONV)
Conditions
Interventions
Sufentanil group:Sufentanil intravenous injection (S)
Tegileridine Fumarate Group (T):Tegileridine fumarate intravenous injection
Sponsors
The First People’s Hospital of Lianyungang
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Female patients diagnosed with gallstones preoperatively and deemed suitable for laparoscopic surgery; 2. According to the American Society of Anesthesiologists (ASA) classification criteria: patients classified as grades 1-3 were selected; 3. Age range 18-65 years old; 4. The surgery duration should not exceed 3 hours, and the intraoperative blood loss; 5. The patient voluntarily participated and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with malignant tumors, severe cardiovascular and cerebrovascular diseases, impaired liver or kidney function, and mental disorders; 2. For those with organic lesions, corresponding symptoms were already present before surgery; 3. Individuals with a known history of allergy to any component of the investigational drug, or those allergic to or with contraindications for the anesthesia/analgesic medications used in the study; 4. Individuals with intellectual disabilities, communication disorders, or mental illnesses;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nausea and vomiting within 1 day after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs during tracheal intubation;Postoperative hospital stay length, patient satisfaction;VAS scores at rest and during exercise 24 hours postoperatively.;Vital signs 5 minutes after extubation;Postoperative Day 1 I-FEED Score;Basic Vital Signs; | — |
Countries
China
Contacts
Public ContactQian Haitao
The First People’s Hospital of Lianyungang
Outcome results
None listed