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Prospective study on the mechanism of brain injury in patients with pulmonary hypertension based on "lung brain axis"

Prospective study on the mechanism of brain injury in patients with pulmonary hypertension based on "lung brain axis"

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600125306
Enrollment
Unknown
Registered
2026-05-25
Start date
2025-04-30
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary hypertension

Interventions

Pulmonary hypertension group:NA
Healthy people group:NA

Sponsors

Beijing Chaoyang Hospital Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: According to the 2022 esc/ers guidelines for the diagnosis and treatment of pulmonary hypertension, PAH was diagnosed.

Exclusion criteria

Exclusion criteria: (1) Did not sign the informed consent for this test; (2) Contraindications to magnetic resonance imaging (pacemaker/defibrillator implantation, claustrophobia or any prohibited procedure Clinical status of long-term MRI examination); (3) Complicated with epilepsy, cerebrovascular disease, etc; (4) Complicated with mental illness.

Design outcomes

Primary

MeasureTime frame
Brain MRI;Mean Pulmonary artery pressure;Cardiac output;—

Secondary

MeasureTime frame
pCO2(mmHg);pO2(mmHg);SO2(%);6MWD;BNP/NT-proBNP(ng/L);PAH hazard stratification;Cognitive function score;General demographic data;CI(L/min/m2);Ejection fraction;PVR;—

Countries

China

Contacts

Public ContactQi Yang

Beijing Chaoyang Hospital Affiliated to Capital Medical University

15955180982@163.com+86 159 5518 0982

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026