Auditory Comprehension Impairment in Post-Stroke Aphasia
Conditions
Interventions
Patient group:None
Healthy control group:None
Sponsors
Zhejiang Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Clinical diagnosis is cerebral infarction, confirmed by cranial CT or MRI examination. The diagnostic criteria must comply with the "Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018". 2.This onset is the first occurrence of a stroke, and the condition is stable, with a course of 1-3 months; 3.Age range: 18-75 years; 4.Years of education: >= 6 years; 5.Native language: Chinese; 6.Presence of Aphasia: Aphasia quotient (AQ) of the Western Aphasia Battery (WAB) <93.8; 7.There is a listening comprehension disorder: determined to be Wernicke's aphasia according to WAB; 8.The standard Chinese version of the handedness evaluation form indicates a right-handed preference, meaning the dominant hemisphere is the left hemisphere;
Exclusion criteria
Exclusion criteria: 1.There is a history of visual or auditory impairments, or a history of neurological and psychiatric disorders such as dementia or speech disorders; 2.History of alcohol or psychoactive substance abuse; 3.There was widespread cognitive impairment at enrolment, making it impossible to cooperate with neuropsychological scale assessments; 4.There was widespread cognitive impairment at enrolment, making it impossible to cooperate with neuropsychological scale assessments; 5.Conventional MRI sequences revealed asymptomatic brain infarctions and other old neurological lesions; 6.There are contraindications for MRI examinations, such as implanted metal devices or claustrophobia;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Magnetic resonance functional connectivity strength;WAB Scale Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| ADL score; | — |
Countries
China
Contacts
Public ContactJie Zhang
Zhejiang Provincial People's Hospital
Outcome results
None listed