Intestinal polyp
Conditions
Interventions
Remimazolam group:During the induction period, intravenous injection of alfentanil 7 µg/kg should be administered, pushed over more than 10 seconds. After 30 seconds, slowly inject remimazolam besylat
Propofol group:During the induction period, administer a slow intravenous injection of alfentanil at 7 µg/kg, pushing over more than 10 seconds. After 30 seconds, slowly inject propofol injection intr
additionally, give propofol at 0.2 mg/kg (push over 10 seconds) every 10 minutes or when the patient shows movements during surgery or noticeable swallowing actions, until stabilization is achieved. T
Sponsors
Longquanyi District First People's Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for elective painless colorectal polypectomy; 2. Aged 18 to 60 years, any gender; 3. Body Mass Index (BMI): 18–28 kg/m²; 4. American Society of Anesthesiologists (ASA) Physical Status Classification: I–III;
Exclusion criteria
Exclusion criteria: 1. Subjects who explicitly refuse to participate in this study; 2. Patients with abnormal liver or kidney function; 3. Those allergic to opioids, benzodiazepines, propofol, flumazenil, or naloxone excipients; 4. Use of ß-blockers, anti-anxiety drugs, or antidepressants; 5. Electrocardiogram indicating: heart rate 100 beats/min, or severe arrhythmia; 6. History of acute respiratory infection within 1 week that has not been cured; 7. History of severe heart, brain, lung, liver, kidney, or metabolic diseases, neuromuscular system diseases (e.g., myasthenia gravis), or psychiatric disorders; 8. Preoperative hypertension with systolic blood pressure > 180 mmHg and/or diastolic blood pressure > 110 mmHg, or hypotension < 90/60 mmHg; 9. Other subjects whom the researchers deem unsuitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SPO2;Mean arterial pressure; | — |
Countries
China
Contacts
Public ContactQiang Zhang
Longquanyi District First People's Hospital)
Outcome results
None listed