Vascular aging, Cerebral arteriosclerosis, Cerebral insufficiency
Conditions
Interventions
Intervention Group:Provide guidance throughout the process and implement interventions to reduce prolonged sitting
control group:Provide a regular guidance
Sponsors
The First Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 60 years old. 2. No diseases affecting standing, such as lumbar disc herniation and knee arthritis. 3. At enrollment, vascular sclerosis or slightly hardened blood vessels were indicated by pulse wave velocity (PWV) detection, and the comprehensive score indicated by cardiovascular function assessment (CVFA) is less than 90. 4. Voluntary willing to comply with the study protocol and sign the informed consent form. 5. Self-reported daily sedentary time exceeded 10 hours.
Exclusion criteria
Exclusion criteria: 1. Participation in other exercise rehabilitation programs within the past six months or ongoing participation at the time of enrollment. 2. Inability to comply with follow-up assessments due to illiteracy, dementia, impaired mobility, or other related conditions. 3. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the comprehensive score of the CVFA examination; | — |
Secondary
| Measure | Time frame |
|---|---|
| hs-CRP;self-reported daily sedentary time;mean blood flow (Qmean);Changes in body composition analysis;IL-6;critical pressure (CP);peripheral resistance (Rv);vascular characteristic impedance (Zcv);mean blood flow velocity (Vmean);pulse wave velocity (PWV);differential pressure (DP);maximum blood flow velocity (Vmax);dynamic resistance (DP);minimum blood flow velocity (Vmin); | — |
Countries
China
Contacts
Public ContactHong Hua
The First Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed