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A study on the construction of a clinical prognosis model for double-expression lymphoma based on 18F-FDG PET/CT multimodal imaging and pathological features

A study on the construction of a clinical prognosis model for double-expression lymphoma based on 18F-FDG PET/CT multimodal imaging and pathological features

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600125272
Enrollment
Unknown
Registered
2026-05-25
Start date
2026-05-25
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Double-Expressor Lymphoma

Interventions

Observation group:None

Sponsors

Chongqing University Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age range: 18 - 80 years old, gender not restricted; 2. Confirmed double-expression lymphoma: having overexpression of both c-Myc and Bcl-2 proteins, while fluorescence in situ hybridization analysis did not show gene rearrangement in diffuse large B-cell lymphoma; 3. Complete medical history including 18F-FDG PET/CT, clinical and pathological data.

Exclusion criteria

Exclusion criteria: 1. Presence of two or more concurrent malignant tumors; 2. Incomplete medical history data; 3. The investigator considers that the subject may not be able to complete the study or comply with the study requirements (due to administrative or other reasons).

Design outcomes

Primary

MeasureTime frame
PET/CT related parameters (SUVmax, SUVpeak, Dmaxbulk, Dmaxpatient, BVG, etc.; measurement of Euclidean distance, Manhattan distance, Chebyshev distance);Clinical indicators ( IPI score, LDH level, age, Ann Arbor stage, treatment plan, etc.);Pathological features (c-Myc, Bcl-2, Ki-67, CD5, TP53, etc.);

Countries

China

Contacts

Public ContactXiaoliang Chen

Chongqing University Cancer Hospital

928862116@qq.com+86 23 65070529

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026