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Mediating role of inflammation in the association between the uric acid to high-density lipoprotein cholesterol ratio and cardiorenal syndrome: insights from NHANES and external validation

Mediating role of inflammation in the association between the uric acid to high-density lipoprotein cholesterol ratio and cardiorenal syndrome: insights from NHANES and external validation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600125261
Enrollment
Unknown
Registered
2026-05-24
Start date
2026-05-30
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiorenal Syndrome

Interventions

Cardiorenal syndrome group vs non-cardiorenal syndrome group:None

Sponsors

Ningbo Medical Centre Lihuili Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients admitted to Ningbo Medical Center Lihuili Hospital between 2015 and 2017.

Exclusion criteria

Exclusion criteria: 1. Individuals with incomplete or unreliable data. 2. Age < 20 years.

Design outcomes

Primary

MeasureTime frame
Uric acid to high-density lipoprotein cholesterol ratio (UHR);Cardiorenal Syndrome(CRS);—

Secondary

MeasureTime frame
NLR (Neutrophil-to-Lymphocyte Ratio);systemic immune-inflammation index (SII);PLR ( Platelet-to-Lymphocyte Ratio);—

Countries

China

Contacts

Public ContactChen Zhuikui

Ningbo Medical Centre Lihuili Hospital

czk3231@163.com+86 574 87018591

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026