None
Conditions
Interventions
Normal Saline Group:Normal saline spray was evenly administered into both nostrils of the patients 30 minutes before the operation.
Dexmedetomidine Nasal Spray Group:Dexmedetomidine nasal spray was evenly administered into both nostrils of the patients 30 minutes before the operation.
Sponsors
Quzhou People Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age: 18 to 70 years old; 2. American Society of Anesthesiologists (ASA) Physical Status Classification I to III; 3. scheduled for flexible bronchoscopy; 4. Preoperative liver and kidney function test results within the normal reference range, with no definite surgical or anesthetic contraindications; 5. No cardiovascular diseases such as significant ST-T segment changes on electrocardiogram or severe arrhythmia; 6. Patients and their family members have been informed of the study and provided informed consent to participate.
Exclusion criteria
Exclusion criteria: 1. Patients with nasal administration contraindications such as nasal anatomical abnormalities or a history of epistaxis, or those who refuse to receive nasal administration; 2. Body Mass Index (BMI) 30 kg/m²; 3. Resting heart rate Grade III; 6. Intraoperative occurrence of active massive hemorrhage (blood loss > 100 mL) or malignant arrhythmia requiring emergency treatment; 7. Patients currently participating in other clinical trials; those deemed unsuitable for the clinical trial by researchers due to other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preoperative Anxiety Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ramsay Sedation Scale;The occurrence of anesthesia-related adverse reactions;Time to Discharge from Post-Anesthesia Care Unit (PACU) and Discharge Score (Aldrete Score);Oxygen saturation, blood pressure and heart rate change; | — |
Countries
China
Contacts
Public ContactFang Xiangyu
Quzhou People Hospital
Outcome results
None listed