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A Multidisciplinary-Based Short-Term Prehabilitation Strategy for Frail Elderly Patients Undergoing TAVR

A study on the safety and efficacy of multidisciplinary preoperative rehabilitation for elderly frail patients undergoing transcatheter aortic valve replacement (TAVR)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600125252
Enrollment
Unknown
Registered
2026-05-22
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

valvular heart disease

Interventions

control group:Routine treatment
intervention group:The intervention group added the "preoperative rehabilitation nursing intervention model based on multidisciplinary care for elderly frail valve-injecting patients" on top of the ro

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Age greater than 65 years; 2. Evaluated by a multidisciplinary team and meeting the indications for TAVR surgery, intending to undergo elective TAVR surgery; 3. Preoperative assessment indicates a frail state (Basic Frailty Assessment Tool score >= 3 points); 4. Cardiac function classified as NYHA grade I-III; 5. The patient or their legal representative understands this study and signs a written informed consent form.

Exclusion criteria

Exclusion criteria: 1. Severe cognitive dysfunction, mental illness or neuromuscular disorders that prevent participation in rehabilitation training; 2. Received respiratory training or rehabilitation training within 8 weeks; 3. Had preoperative infectious endocarditis or aortic dissection and required mechanical circulatory support (extracorporeal membrane oxygenation, aortic balloon counterpulsation, ventricular assist device); 4. Participated in other clinical intervention studies within the past 3 months; 5. Expected survival period is less than 6 months due to non-cardiac diseases.

Design outcomes

Primary

MeasureTime frame
6-minute walking distance;EQ-5D;

Secondary

MeasureTime frame
Hospital-associated disability, HAD;postoperative complications;

Countries

China

Contacts

Public ContactChen Miao

West China Hospital, Sichuan University

846260052@qq.com+86 189 8060 6107

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026