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Identification of differences in the expression levels of two stress-related biomarkers(GZMB FASLG) between patients with coronary heart disease and the normal people

Identification of biomarkers related to stress granule in coronary heart disease: insights from transcriptomics and experimental validation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600125245
Enrollment
Unknown
Registered
2026-05-22
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The coronary heart disease

Interventions

Coronary Heart Disease Group:None
Control Group:None

Sponsors

The 920 Hospital of the Joint Support Force of the People's Liberation Army of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 60-75 years old; 2. With positive coronary angiography (at least one coronary artery with >=50% stenosis); 3. With negative coronary angiography (all coronary arteries with <50% stenosis).

Exclusion criteria

Exclusion criteria: 1. Patients not between the ages of 60 and 75; 2. Patients with acute and chronic inflammatory diseases, as well as rheumatic and immune-related disorders; 3. Those with a history of long-term use of hormones or immunosuppressants.

Design outcomes

Primary

MeasureTime frame
Granzyme B;FASLG;—

Countries

China

Contacts

Public ContactWang Hui

The 920 Hospital of the Joint Support Force of the People's Liberation Army of China

whthczjyykz@163.com+86 871 6477 4406

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026