Obstructive Sleep Apnea
Conditions
Interventions
normal control group:None
Sponsors
Beijing Friendship Hospital ,Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Age 18–65, no gender limitation; 2.Able to understand the study content and voluntarily sign the informed consent form; 3.Capable of cooperating with the shear wave elastography ultrasound examination of the upper airway during wakefulness and performing the Müller maneuver; 4.OSA subjects must be diagnosed with OSA through PSG or a standardized portable sleep monitoring device. 5.Control subjects had no clear symptoms related to OSA or were excluded for OSA based on sleep monitoring. 6.Possesses complete or substantially complete general clinical data.
Exclusion criteria
Exclusion criteria: 1.Patients who have previously undergone surgery affecting the upper airway structure, such as pharyngeal, tongue, or maxillofacial procedures; 2.Patients with combined head and neck tumors, acute inflammation, obvious structural deformities, or severe temporomandibular joint/oral opening limitations; 3.Patients with neuromuscular disorders, severe cardiopulmonary insufficiency, or other systemic diseases that preclude tolerance of the examination; 4.Pregnant or individuals deemed unsuitable for participation in this study by the investigator; 5.Those unable to perform the Müller maneuver or whose ultrasound image quality does not meet the analysis requirements; 6.Participants who refuse to sign the informed consent form or withdraw from the study midway.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Upper airway collapse phenotype indicators;Shear wave elastography indices of upper airway muscles during wakefulness;Indicators of paired changes between wakefulness and sleep induction period (SWE);Drug-Induced Sleep Endoscopy Subgroup: Shear Wave Elastography of Upper Airway Muscles;Sleep monitoring indicators;Comorbidities and prior treatment information; | — |
Secondary
| Measure | Time frame |
|---|---|
| General clinical indicators;Safety monitoring indicators (assessing discomfort and related adverse events);SWE parameters and combined scores of other regions; | — |
Countries
China
Contacts
Public ContactHou Qian
Beijing Friendship Hospital ,Capital Medical University
Outcome results
None listed