Thyroid Cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. This study included patients who were comprehensively staged as AJCC 8th edition T4a or T4b based on preoperative imaging assessment, intraoperative findings, and postoperative pathological examination, and who were histologically confirmed to have papillary thyroid carcinoma (PTC) after surgery; 2. All patients underwent their initial surgical treatment for thyroid cancer at our hospital; 3. Inclusion criteria were age =18 years; 4. Complete clinical, pathological, surgical, and follow-up data sufficient for prognostic analysis and model construction.
Exclusion criteria
Exclusion criteria: 1. patients who underwent non-primary surgeries or reoperations due to local recurrence or residual disease; 2. patients with other types of thyroid malignancies whose pathological types were not papillary thyroid carcinoma; 3. patients under 18 years of age; 4. patients with missing and irreplaceable clinical data, surgical records, pathological findings, or critical follow-up data; 5. patients with synchronous malignancies that could potentially interfere with survival outcomes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pathological characteristics (including tumor size, multifocality, lymph node metastasis, extent of invasion, molecular pathology such as BRAF and TERT);Treatment characteristics (including surgical approach, lymph node dissection, radioactive iodine therapy, external radiotherapy, etc.);Follow-up data (including recurrence, metastasis, survival status, follow-up duration, outcome events);Postoperative complications and treatment response assessment; | — |
Countries
China
Contacts
West China Hospital of Sichuan University