Interstitial lung disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old, and have signed the informed consent form; 2. Meet the diagnostic criteria for ILD as per international guidelines (such as ATS/ERS), and be confirmed by HRCT and/or lung biopsy; 3. Able to cooperate in completing pulmonary function tests, cardiac imaging examinations and follow-up.
Exclusion criteria
Exclusion criteria: 1. Include other severe heart and lung diseases (such as left heart failure, congenital heart disease, severe COPD, pulmonary embolism); 2. Active malignant tumors or life expectancy less than 1 year; 3. Pregnant or lactating women; 4. Those who cannot complete follow-up or whose data collection is incomplete.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause mortality;Acute exacerbation rate of interstitial lung disease;Right heart failure events (meeting clinical and echocardiographic criteria);Annual decline in pulmonary function (FVC decrease >=10% or DLCO decrease >=15%);Worsening right heart function (e.g., TAPSE decrease >=2 mm, RVSP increase >=10 mmHg); | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life score (SGRQ or K-BILD questionnaire); | — |
Countries
China
Contacts
Shijiazhuang People’s Hospital