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Polytetrafluoroethylene (PTFE) Vascular Grafts for Venous Reconstruction in Hepatobiliary and Pancreatic Surgery: A Retrospective Cohort Study Protocol

Polytetrafluoroethylene (PTFE) Vascular Grafts for Venous Reconstruction in Hepatobiliary and Pancreatic Surgery: A Retrospective Cohort Study Protocol

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600125198
Enrollment
Unknown
Registered
2026-05-22
Start date
2026-05-28
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatobiliary-pancreatic diseases

Interventions

Observation group:None

Sponsors

The First Affiliated Hospital of Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >=18 years, regardless of gender; 2. Surgical procedure performed between January 2020 and December 2026; 3. Operation conducted by the Department of Hepatobiliary Surgery; 4. Intraoperative use of PTFE vascular grafts for various types of venous reconstruction, including interposition grafting, shunting, bypass, combined reconstructions, and hepatic outflow tract reconstruction (hepatic veins/retrohepatic inferior vena cava); 5. At least one postoperative contrast-enhanced CT or MRI examination completed for graft patency assessment; 6. Detailed operative documentation of reconstruction type, PTFE specifications, anastomotic technique, and intraoperative circumstances.

Exclusion criteria

Exclusion criteria: 1. Emergency procedures such as traumatic injuries or ruptured hemorrhage; 2. Isolated arterial reconstruction without venous system involvement; 3. Venous resection without reconstruction, such as simple splenic vein ligation; 4. Intraoperative abandonment of PTFE reconstruction due to technical reasons with conversion to alternative materials; 5. Loss of critical clinical data exceeding 30%, precluding confirmation of reconstruction type or graft material; 6. Absence of postoperative imaging follow-up precluding patency evaluation; 7. Early periprocedural mortality defined as death within 7 postoperative days, preventing graft function assessment; 8. Use of PTFE patch angioplasty alone without tubular reconstruction.

Design outcomes

Primary

MeasureTime frame
Cumulative patency rate of PTFE grafts;

Secondary

MeasureTime frame
Safety indicators (including all-cause mortality and PTFE-related mortality within 90 days after surgery);Complication outcomes;Functional and oncological outcomes;PTFE-specific outcomes;

Countries

Guangxi

Contacts

Public ContactWen Zhang

The First Affiliated Hospital of Guangxi Medical University, 6 Shuangyong Road, Nanning,

hwt18260818385@163.com+86 138 7810 8107

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026