Postoperative sleep disorders in patients with thyroid cancer
Conditions
Interventions
Group L:Before anesthesia induction, 0.3mg/kg of esketamine was intravenously injected.
Group H:Before anesthesia induction, 0.5mg/kg of esketamine was intravenously injected.
Group C:Intravenous injection of an equal amount of normal saline before anesthesia induction
Sponsors
Affiliated Hospital of Zunyi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-60 years old, gender unrestricted; 2. ASA classification grade I - II; 3. BMI 18-28 kg/m^2; 4. Informed consent to the surgical and anesthesia plans, voluntarily signing the surgical informed consent form and the anesthesia informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe insomnia symptoms before the operation, with a preoperative Pittsburgh Sleep Quality Index (PSQI) > 7; 2. History of thyroid surgery, hyperthyroidism or hypothyroidism; 3. Severe organic lesions in heart, lung, liver and kidney functions [combined with abnormal functions of important organs such as heart, liver and kidney (NYHA classification > grade 2; liver failure or Child-Pugh score B or C; glomerular filtration rate < 30 ml/min)]; 4. Previously diagnosed with mental disorders; 5. Those with contraindications to general anesthesia and esketamine injection; 6. Long-term (at least 3 consecutive months) use of opioid drugs, sedative drugs, antidepressant drugs or anti-anxiety drugs; 7. Patients who refuse to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Athens Insomnia , AIS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Richards-Campbell Sleep , RCSQ;Hospital Anxiety and Depression ,HADS;Numerical Rating , NRS; | — |
Countries
China
Contacts
Public ContactZhang Hong
Affiliated Hospital of Zunyi Medical University
Outcome results
None listed