There are non-tumor diseases with possible high expression of FAP, including but not limited to:(1) Inflammatory/immune disorders: Inflammatory bowel disease (IBD), IgG4-related diseases, rheumatoid arthritis, vasculitis.(2) Fibrotic diseases: Idiopathic pulmonary fibrosis (IPF), interstitial lung disease (ILD), liver fibrosis, retroperitoneal fibrosis.Cardiovascular system diseases: Ventricular r
Conditions
Interventions
Gold Standard:Detection of FAP expression by pathological IHC method
Index test:18F/68Ga/64Cu-FAPI PET scan
Sponsors
Shanghai tenth People's Hospital
Eligibility
Sex/Gender
All
Age
19 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Age range: 18 - 75 years old. Gender: No restrictions. 2.Suspected presence of non-tumor lesions with high expression of FAP; 3.Expected survival period >= 6 months; 4. Understand the purpose of the study and the associated risks, voluntarily sign a written informed consent form, and demonstrate good compliance.
Exclusion criteria
Exclusion criteria: 1.Pregnant or lactating women; 2.Those who were diagnosed with concurrent malignant tumors at the same time and whose conditions were not under control; 3.Severe restlessness, unable to cooperate for a long period (approximately 20 minutes) of quiet and lying still examination. 4.Severe liver and kidney dysfunction; 5.Those who are allergic to the components of the developer or have other contraindications;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Specificity;Accuracy;Sensitivity; | — |
Countries
China
Contacts
Public ContactChao Ma
Shanghai tenth People's Hospital
Outcome results
None listed