Multiple pulmonary nodules
Conditions
Interventions
sham stimulation group:Sham transcutaneous auricular vagus nerve stimulation (sham taVNS)
Sponsors
The Fourth Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 59 Years
Inclusion criteria
Inclusion criteria: 1. Age 18 to 59 years. 2. Patients diagnosed with multiple pulmonary nodules by thoracic surgeons based on chest CT findings, with clear surgical indications and already scheduled for elective surgery. 3. American Society of Anesthesiologists (ASA) physical status classification I–III. 4. Sufficient cognitive ability to complete anxiety assessment scales and perioperative follow-up. 5. Voluntary participation and provision of signed informed consent.
Exclusion criteria
Exclusion criteria: 1. History of psychiatric or neurological disorders. 2. Long-term use of corticosteroids, antidepressants/anxiolytics, sedatives, or analgesics. 3. Concomitant severe neurological, renal, cardiovascular, or hepatic diseases. 4. Ear skin breakdown or infection, posing contraindications to transcutaneous auricular vagus nerve stimulation. 5. Presence of a cardiac pacemaker or other electronic implantable devices.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Anxiety Scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Recovery-15 (QoR-15) scale;Pittsburgh Sleep Quality Index (PSQI);Pain Numerical Rating Scale (NRS) score; | — |
Countries
China
Contacts
Public ContactHuaqin Liu
The Fourth Hospital of Hebei Medical University
Outcome results
None listed