Orbital apex space-occupying position
Conditions
Interventions
Operation group:Endoscopic removal of superolateral orbital apex lesions via a transconjunctival (inferior fornix) extra-periosteal approach.
Sponsors
Eye Hospital, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age =18 years; both sexes included; 2. Patients presenting with symptoms such as decreased vision, blurred vision, diplopia, ocular distension, orbital pain, exophthalmos, optic nerve atrophy, limited extraocular abduction, headache, or dizziness all underwent orbital computed tomography (CT) to define the relationship between the space-occupying lesion (including tumors and foreign bodies, etc.) and the surrounding anatomical structures, and to confirm that the lesion was located at the orbital apex superolateral to the optic nerve. For non-metallic foreign bodies or tumors, cranial magnetic resonance imaging (MRI) could be combined for further evaluation; whereas for metallic foreign bodies, only orbital CT was performed to confirm the lesion's location at the orbital apex superolateral to the optic nerve; 3. The patients and their families have given informed consent to this study, fully understand the safety of the research project, are willing to actively cooperate with the study, accept the surgical method of this project, and can cooperate with the follow-up requirements in the future, and have signed an informed consent form; 4. Complete data, including preoperative ocular CT and MRI images (MRI contraindications should be noted for patients with foreign bodies), optic disc OCT, and VEP, etc.
Exclusion criteria
Exclusion criteria: 1. Various imaging techniques and vascular puncture angiography have been used to diagnose an unclear lateral mass of the optic nerve; 2. Preoperative radiation therapy, surgical treatment, or chemotherapy for the disease; 3. The subjects themselves have eye diseases that affect visual function, such as keratitis and thyroid related eye diseases; 4. Pregnant and lactating women; 5. Serious systemic diseases such as heart, lung, liver, and kidney dysfunction; 6. Other situations that are not suitable for surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Best corrected visual acuity;Eye Movement Function;Intraocular pressure;Eye protrusion degree;Cranial MRI examination;Orbital CT examination; | — |
Secondary
| Measure | Time frame |
|---|---|
| Eye ultrasound;Eye Photography;OCT/OCTA;Visual evoked potential;Vision field;Fundus photography; | — |
Countries
China
Contacts
Public ContactTu Yunhai
Eye Hospital, Wenzhou Medical University
Outcome results
None listed