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Model Development and Validation for New-Onset Ischemic Stroke in Patients with Left Atrial Appendage Thrombus

Model Development and Validation for New-Onset Ischemic Stroke in Patients with Left Atrial Appendage Thrombus

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600125139
Enrollment
Unknown
Registered
2026-05-21
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Left Atrial Appendage Thrombus

Interventions

Modeling group (The First Affiliated Hospital of Dalian Medical University):None
Validation group (Linyi People's Hospital):None

Sponsors

The First Affiliated Hospital of Dalian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Consecutively enrolled hospitalized patients who were found to have left atrial appendage (LAA) thrombus on cardiac contrast-enhanced CT imaging (including atrial, pulmonary vein CT, and coronary CT angiography) at the Department of Cardiology of the First Affiliated Hospital of Dalian Medical University and the Department of Medical Imaging of Linyi People's Hospital between February 1, 2015 and January 1, 2025.

Exclusion criteria

Exclusion criteria: 1. Patients with diseases such as patent foramen ovale, left atrial myxoma, or severe valvular heart disease; 2. Patients with chest trauma, major surgery, or severe infection within the past 3 months; 3. Patients with severe liver or kidney dysfunction; 4. Patients hospitalized due to immune system disorders, hematological diseases, or end-stage malignant tumors; 5. Bedridden patients or those unable to communicate verbally.

Design outcomes

Primary

MeasureTime frame
Incidence rate of symptomatic ischemic stroke;Symptomatic ischemic stroke occurrence in patients with left atrial appendage thrombus;

Secondary

MeasureTime frame
Correlation between related risk factors including left atrial appendage morphology and new-onset ischemic stroke in patients with left atrial appendage thrombus;

Countries

China

Contacts

Public ContactDong Yingxue

The First Affiliated Hospital of Dalian Medical University

dongyingxue@firsthosp-dmu.com+86 18098875799

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026