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Evaluation of myocardial microcirculation function in patients with obstructive coronary artery disease using load-based CT myocardial perfusion imaging combined with CT-FFR

Evaluation of myocardial microcirculation function in patients with obstructive coronary artery disease using load-based CT myocardial perfusion imaging combined with CT-FFR

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600125131
Enrollment
Unknown
Registered
2026-05-21
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive coronary heart disease

Interventions

Moderate stenosis group:None
Group with severe stenosis or occlusion:None

Sponsors

The Second Affiliated Hospital of Dalian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Complete imaging data and clinical history data; 2. Age range of 18 to 80 years old; 3. Clinically suspected of obstructive coronary heart disease; 4. Coronary artery non-left main stenosis degree > 70% and/or left main > 50%

Exclusion criteria

Exclusion criteria: 1. Acute coronary syndrome, heart failure, unstable angina pectoris; 2. Have taken psychotropic drugs such as anti-anxiety and anti-depression drugs; 3. Severe renal dysfunction; 4. Allergy to iodine-based contrast agents; 5.Unable to perform stress myocardial perfusion (second- and third-degree atrioventricular block, sinus node dysfunction) ; 6. Any non-left main coronary stenosis less than 70% and/or left main coronary stenosis less than 50%

Design outcomes

Primary

MeasureTime frame
Myocardial perfusion indicators (myocardial blood flow, myocardial blood volume, mean transit time, peak time);Coronary CT-derived fractional flow reserve;

Countries

China

Contacts

Public ContactXiaofeng Qu

The Second Affiliated Hospital of Dalian Medical University

drquxiaofeng@163.com+86 177 0987 5118

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026