None
Conditions
Interventions
Experimental group:30 minutes before the end of the surgery, the experimental group was given Ocesalid at 22 µg/kg
Control group:30 minutes before the end of the surgery, the control group was given sufentanil 0.11 µg/kg
Sponsors
Heze Municipal Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age 60-75 years; 2. BMI 18-26 kg/m^2; 3. ASA classification I-III; 4. Meet the indications for laparoscopic cholecystectomy; 5. Patient voluntarily joins, signs the informed consent, can understand various scoring methods and can cooperate to complete the assessment.
Exclusion criteria
Exclusion criteria: 1. Severe internal or surgical diseases. 2. Abdominal surgical scars, abdominal wall skin infection or damage affecting the spread of local anesthetics; 3. Cancer patients whose pain cannot be effectively controlled by known opioids; 4. Individuals with intellectual disabilities or mental disorders who cannot cooperate with researchers; 5. History of allergy to any investigational drugs in this trial; 6. Abnormal coagulation function or currently receiving thrombolytic or anticoagulant therapy; 7. Patients with diffuse peritonitis; 8. Patients who usually suffer from motion sickness; 9. Individuals who have taken benzodiazepine sedatives or opioid analgesics continuously or intermittently within 24 hours before enrollment; 10. History of gastrointestinal bleeding or perforation, or history of lower abdominal surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality score of 24-hour postoperative recovery; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of postoperative nausea and vomiting;Recovery time of bowel sounds;VAS pain scores at rest and during exercise;Additional dose of opioids;The incidence of adverse events such as respiratory depression; | — |
Countries
China
Contacts
Public ContactSu Chunyu
Heze Municipal Hospital
Outcome results
None listed