pulmonary nodule
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. American Society of Anesthesiologists Classification, Class I to III; 2. Patients aged 18 to 75 years who underwent elective thoracoscopic lobectomy or segmentectomy at our institution; 3. Patients who consented to participate in the study and demonstrated comprehension of relevant assessment items (with voluntarily signed informed consent forms); 4. Body mass index (BMI) ranging from 18.5 to 28 kg/m²;
Exclusion criteria
Exclusion criteria: 1. Contraindications for regional nerve blockade, including but not limited to coagulopathy, infection at the blockade site, and allergy to local anesthetics; 2. Presence of severe organ dysfunction constituting, but not limited to, renal impairment (serum creatinine >442 µmol/L or requirement for renal replacement therapy), hepatic dysfunction (Child-Pugh class C), and major neurological or cardiopulmonary disorders; 3. Patients with a history of chronic pain disorders who required prolonged use of opioid analgesics, corticosteroids, or NSAIDs were excluded; 4. Patients previously enrolled in other clinical studies were excluded;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total Opioid Analgesic Consumption Within 48 Hours Postoperatively (expressed as morphine milligram equivalents, MME); | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of agitation during awakening;Postoperative Thirty-Day Mortality;time to first ambulation after surgery;The time of first PCA and the number of rescue analgesia in 48h after surgery;RASS scores at different postoperative time points (5 min postoperatively, 10 min postoperatively, 15 min postoperatively, 20 min postoperatively, 25 min postoperatively, 30 min postoperatively);time to diet after surgery;VAS scores of rest and activity at different time points after surgery (2h, 4h, 8h, 12h, 24h, 48h);Postoperative drain removal time;Skin sensory block segment 20min after completion of block;Opioid Analgesic Consumption during Predefined Postoperative Intervals;Adverse events of the block;Incidence of Pulmonary Complications Within 30 Days Postoperatively;Duration of surgery;Intraoperative Blood Pressure and Heart Rate at Predetermined Time Points;Postoperative 30-Day Pain Outcomes;Duration of Anesthetic Emergence;Onset Time and Duration of Sensory Block;time to exhaust after surgery;Postoperative nausea and vomiting, puncture site infection, itching and other adverse events;Intraoperative Opioid Analgesic Administration;Intraoperative bleeding;Quality of Recovery-15 (QoR-15) Scores at Preoperative Baseline and Postoperative 24-Hour/48-Hour Intervals;Intraoperative blood gas analysis at different time points (before induction of anesthesia, 1 h into surgery, at the end of surgery);Intraoperative infusion volume; | — |
Countries
China
Contacts
First Affiliated Hospital of Gannan Medical University