Severe pneumonia
Conditions
Interventions
Experimental group:Transcutaneous phrenic nerve and abdominal muscle electrical stimulation
Control group:Conventional treatment
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Meet the diagnostic criteria for severe pneumonia according to the 2019 American Thoracic Society and Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of adults with community-acquired pneumonia. 2.Aged 40 to 80 years. 3.Provide signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Women who are pregnant or lactating. 2. Presence of unhealed wounds, active infection, or skin breakdown in the neck, upper chest, or abdominal area. 3. Bleeding tendency or coagulation dysfunction (confirmed by clinical assessment or laboratory tests indicating significant bleeding risk, such as platelet count 3 times the upper limit of normal, eGFR = III, or other conditions judged by the investigator to pose significant risks). 5. Presence of an implanted cardiac pacemaker, implantable cardioverter-defibrillator (ICD), or other electronic implantable devices. 6. Unhealed wounds after thoracic or abdominal surgery. 7. Individuals with reduced skin sensation, impaired skin perception, or skin abnormalities (e.g., easily irritated skin, local skin damage, infection, scar hyperplasia affecting electrode placement). 8. Severe cognitive impairment that precludes cooperation with treatment, unconsciousness, joint contracture deformities of the limbs, or severe contracture deformities due to osteoarthritis. 9. Presence of metal implants in the eyes, cardiac region, or carotid sinus area, or local lesions requiring avoidance of electrical stimulation. 10. Inability to provide informed consent, or deemed unsuitable for participation by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood gas parameters;Clinical Pulmonary Infection Score;Inflammatory markers;Oxygenation index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Rapid Shallow Breathing Index;Mortality rate;Duration of mechanical ventilation during ICU stay;Length of ICU stay; | — |
Countries
China
Contacts
Public ContactFeng Min
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed