depressive disorder / depressive disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Disease Group: 1. Age 18-55 years old; 2. Meets the diagnostic criteria of the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) for depressive disorders, primary insomnia, and secondary insomnia caused by depressive episodes, and confirmed by two attending psychiatrists or above; 3. Duration of insomnia >= 3 months; 4. ISI total score >= 15; 5. Education level >= 9 years, normal vision and hearing (or corrected), with normal reading and writing ability to complete scale assessments; 6. No systematic use of psychiatric medications in the past month; 7. Voluntarily participates in this study and signs written informed consent. Control Group: 1. Age 18-55 years old; 2. Matched with the disease group by age (±3 years) and same gender; 3. Education level >= 9 years; 4. Normal vision and hearing (or corrected), no color weakness or color blindness; 5. Voluntarily participates in the study and signs informed consent.
Exclusion criteria
Exclusion criteria: 1. Other mental disorders meeting DSM-5 diagnostic criteria: bipolar disorder, schizophrenia, alcohol and drug dependence, phobias, acute stress disorder, and post-traumatic stress disorder, etc.; 2. Immune and endocrine diseases, cerebrovascular diseases, tumors, severe heart, liver, kidney, and other diseases, and infectious diseases that occurred in the past two weeks; 3. Accompanied by mental retardation or other organic brain diseases, presence of organic auditory or/and visual perception disorders; IQ below 85; 4. Women who are pregnant or breastfeeding; 5. Taken psychiatric medications within the past month; 6. Received physical modulation treatments such as tDCS, tACS, TMS, or non-convulsive electroconvulsive therapy in the past 6 months; 7. Other conditions deemed by the researcher to be unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Insomnia Severity Index (ISI);cueing-effect;Functional structure and functional changes of the brain; | — |
Countries
China
Contacts
Beijing Huilongguan Hospital Affiliated to Capital Medical University