keratoconus
Conditions
Interventions
Case Group:None
Sponsors
Eye Hospital, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 45 Years
Inclusion criteria
Inclusion criteria: 1. The proband must have at least one eye diagnosed with primary keratoconus; 2. The family pedigree must include at least the proband and both parents (a minimum of 3 participants); 3. All participating family members have agreed to participate in this study.
Exclusion criteria
Exclusion criteria: 1. The proband is diagnosed with non-primary keratoconus, e.g., secondary keratoconus; 2. The number of participating family members is insufficient to meet the study requirements; 3. The clinical data or biological samples from the family participants are missing, failing to meet the study requirements.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| genetic locus;corneal signs, corneal topography, corneal biomechanics; | — |
Countries
China
Contacts
Public ContactShihao Chen
Eye Hospital, Wenzhou Medical University
Outcome results
None listed