None
Conditions
Interventions
A group:The patients received a standardized general anesthesia protocol (induction: propofol, rocuronium, sufentanil
maintenance: sevoflurane/propofol, remifentanil), and were routinely administered a patient-controlled analgesia (PCA) pump postoperatively. Upon entering the post-anesthesia care unit (PACU), they we
B group:The patients received a standardized general anesthesia protocol (induction: propofol, rocuronium, and sufentanil
maintenance: sevoflurane/propofol and remifentanil) and were routinely equipped with a patient-controlled analgesia (PCA) pump postoperatively. After entering the post-anesthesia care unit (PACU), the
C group:The patients received a standardized general anesthesia protocol (induction: propofol, rocuronium, and sufentanil
maintenance: sevoflurane/propofol and remifentanil) and were routinely equipped with a patient-controlled analgesia (PCA) pump postoperatively. Upon entering the post-anesthesia care unit (PACU), they
Sponsors
Hainan General Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age = 60 years, any gender 2. ASA classification I-II 3. Planned elective general anesthesia surgery (surgery duration 2-4 hours) 4. BMI 18.5-30 kg/m^2 5. Preoperative MMSE score >= 24 points (no cognitive impairment) 6. Signed written informed consent, able to understand and cooperate with the study procedures
Exclusion criteria
Exclusion criteria: 1. Known or suspected difficult airway (Mallampati class IV, thyromental distance 1.5, platelets <50×10^9/L); 6. Participation in other clinical trials within the past 3 months; 7. Other conditions deemed unsuitable for participation in this study by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rSO2;The minimum value of rSO2;The area under the rSO2curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Diaphragmatic mobility;SpO2;BIS;Awakening Score sheet;Riker Sedative-Restlessness score;The duration from the end of anesthesia to extubation; | — |
Countries
China
Contacts
Public ContactWang Na
Hainan General Hospital
Outcome results
None listed