None listed
Conditions
Interventions
Trial group: remimazolam was chosen as sedative drugs for anesthesia introdution and maintenance
Control group:propofol was chosen as sedative drugs for anesthesia introdution and maintenance
Sponsors
The Second Nanning People's Hospital (The Third Affiliated Hospital of Guangxi Medical University)
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age 18~60 years; 2. ASA class I~II 3.18 kg/m^2< BMI<28Kg/m^2.
Exclusion criteria
Exclusion criteria: 1. Those who are allergic or contraindicated to drugs necessary for this study; 2. Poorly controlled severe hypertension, defined as systolic blood pressure >=180 mmHg, or diastolic blood pressure >=105 mmHg. Meet any one of the requirements above. 3. Second-degree and third-degree atrioventricular block,severe Arrhythmia, and unstable angina; 4. Patients with acute respiratory infection and asthma attack, patients with obvious airway difficulties; 5. A history of long-term use of anesthetic or antipsychotic drugs, alcohol dependence; 6. Participation in other medications within 3 months Clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sedation success rate;Total amount of remifentanil;Adverse events; | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of remedial sedation; The systolic blood pressure of two groups;The diastolic blood pressure of two groups; The heart rate of two groups;Anesthesia induction time;Surgical time; Postoperative wakefulness time; | — |
Countries
China
Contacts
Public ContactYuhua Zhou
The Second Nanning People's Hospital (The Third Affiliated Hospital of Guangxi Medical University)
Outcome results
None listed