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Mechanism of transcranial magnetic stimulation regulating the trans hemispheric reorganization of motor network after stroke

Mechanism of transcranial magnetic stimulation regulating the trans hemispheric reorganization of motor network after stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600125046
Enrollment
Unknown
Registered
2026-05-20
Start date
2026-05-28
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Ipsilateral M1 excitatory TMS:Affected side M1 10Hz rTMS
Excitatory TMS of ventral premotor area on the affected side:Affected ventral premotor area 10Hz rTMS
Contralateral M1 excitatory TMS:Contralateral M1 10Hz rTMS
Contralateral M1 inhibitory TMS:Contralateral M1 cTBS

Sponsors

Ningxia Hui Autonomous Region Hospital of integrated traditional Chinese and Western Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The first occurrence of cerebral infarction confirmed by CT or MRI; 2. Age 18-80 years; 3. The course of disease was 1 week to 6 months; 4. Motor dysfunction, Fugl-Meyer score < 85; 5. The patients and their families were informed and agreed to this study.

Exclusion criteria

Exclusion criteria: 1. Unable to stay awake and cooperate with clinical examinations; 2. CT or MRI shows multiple strokes or brain injuries, and other neurological diseases, psychiatric disorders, or severe spinal diseases are present; 3. MMSE score < 10 points; 4. Severe disability of the affected limb; 5. Recent use of tricyclic antidepressants or sedatives; 6. Epileptic seizures and history of epilepsy; 7. Presence of metal implants in the body (such as cochlear implants, pacemakers, intracranial arterial stents, intracranial vascular coils, ventriculoperitoneal shunts, insulin pumps, etc.) or contraindications to MRI; 8. Significant aphasia and comprehension disorders.

Design outcomes

Primary

MeasureTime frame
EEG cortical potential amplitude changes;Interhemispheric FA value of motor network;

Countries

China

Contacts

Public ContactLinlin Ye

Ningxia Hui Autonomous Region Hospital of integrated traditional Chinese and Western Medicine

happinesslin@163.com+86 951 392 3057

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026