infection
Conditions
Interventions
Sponsors
Shandong Provincial Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Hospitalized patients with confirmed or suspected Gram-positive bacterial infection (such as staphylococcus, streptococcus, Enterococcus, corynebacterium, etc.) can include various types of infection, such as bloodstream infection, infective endocarditis, respiratory system infection, abdominal infection, skin and soft tissue infection, bone and joint infection, central nervous system infection, and urinary tract infection. 2. Use of study drugs: (norepinephrine) vancomycin or teicoplanin or linezolid or daptomycin; 3. No age limit; 4. Gender is not limited; 5. No race limit.
Exclusion criteria
Exclusion criteria: 1. Use of the initial target drug for less than three days; 2. Insufficient data before and after treatment were available for efficacy evaluation.; 3. The patient had used the target drug in another hospital at the time of this infection. 4. Non-standard route of administration, such as vancomycin for irrigation; 5. Other drugs of this study were combined at the same time. 6. Patients or their families refused to sign informed consent to participate in the study. 7. Use of other study drugs was preceded by use of the target drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The clinical effective rate at the end of treatment of the study drug; | — |
Secondary
| Measure | Time frame |
|---|---|
| Efficacy evaluation on the 3rd/4th day;Safety endpoint evaluation;All-cause mortality rate within 28 days;Healing verification test; | — |
Countries
China
Contacts
Public ContactZhang Yahui
Shandong Provincial Hospital
Outcome results
None listed