lymphatic leakage after axillary lymph node dissection for breast cancer
Conditions
Interventions
Experimental group:Carboxymethyl cellulose patches are adhered to the operation field after ALND.
Control group:conventional treatment
Sponsors
The First Affiliated Hospital of Zhejiang Chinese Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Female patients aged between 18 and 70 years (inclusive); 2. Pathologically confirmed invasive breast cancer; 3. Patients scheduled to undergo axillary lymph node dissection for breast cancer; 4. Subjects who voluntarily agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with known allergy to regenerated cellulose or its components (e.g., cellulose, oxidized groups, etc.); 2. Patients with other concurrent malignant tumors (e.g., lung cancer, gastric cancer, etc.) or distant metastasis of breast cancer; 3. Patients with coagulation disorders or active infections; 4. Patients with a history of prior axillary surgery; 5. Patients with severe dysfunction of vital organs (e.g., heart, lung, liver, kidney, brain) who cannot tolerate surgery or study intervention; 6. Patients with psychiatric disorders, cognitive impairment, or those unable to communicate effectively or comply with follow-up; 7. Pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative lymphatic leakage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Drainage fluid triglyceride and cholesterol concentration ;Extubation time;Duration of hospital stay ;Drainage volume daily;Incisional infection rate; | — |
Countries
China
Contacts
Public ContactXu Xiaohong
The First Affiliated Hospital of Zhejiang Chinese Medical University
Outcome results
None listed