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The role and electrophysiological mechanism of response inhibition in non-suicidal self-injury behaviors of adolescents with depression

The role and electrophysiological mechanism of response inhibition in non-suicidal self-injury behaviors of adolescents with depression

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600125029
Enrollment
Unknown
Registered
2026-05-20
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MDD with non-suicidal self-injury

Interventions

Intervention group:Anode tDCS stimulates the right IFG
Control group:Sham stimulation tDCS stimulation right IFG

Sponsors

Fourth People's Hospital of Wuhu
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 18 Years

Inclusion criteria

Inclusion criteria: Adolescents with NSSI Behavioral Depression (MDD-NSSI+) : (1) Meeting the DSM-5 diagnostic criteria for major depressive disorder and NSSI behaviors; (2) Age: 12-18 years old, male or female; (3) The score of the Adolescent Self-Injury Scale is > 10 points, and one of the items is more than 5 times, and the HAMD score is >= 17 points; (4) Normal visual acuity or corrected visual acuity, able to complete neuroelectrophysiological experimental tasks; (5) All enrolled subjects must obtain the consent of their parents or other legal guardians and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Brain injury and other major physical diseases; (2) Mental retardation, epilepsy, and other major neurological disorders; (3) Those who have previously received physical interventions such as MECT, rTMS, tACS, as well as psychological interventions.

Design outcomes

Primary

MeasureTime frame
Adolescent Self-Harm Behavior Scale;Emotional Go/No-Go tasks;

Secondary

MeasureTime frame
Hamilton Depression Scale;Emotion Reactivity Scale;

Countries

China

Contacts

Public ContactFangfang Chen

Fourth People's Hospital of Wuhu

spychen1992@126.com+86 182 2553 8625

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026