recurrent primary spontaneous pneumothorax
Conditions
Interventions
Intervention Group:Treatment with APC Combined with Human Albumin Medical Adhesive via Medical Thoracoscopy
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
14 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 14 and 50 years; 2. A chest X-ray or CT scan from the current visit shows unilateral pneumothorax; 3. A chest CT scan shows pulmonary bullae on the affected side; 4. The air leak has persisted for more than 3 days; 5. History of pneumothorax on the same or opposite side.
Exclusion criteria
Exclusion criteria: 1. Imaging findings indicating a pulmonary bulla with a diameter =5 cm; 2. History of prior surgery on the same side of the chest or pleural fixation; 3. Tension pneumothorax; 4. Secondary spontaneous pneumothorax (i.e., iatrogenic, traumatic, or caused by underlying pulmonary disease); 5. Bilateral pneumothorax; 6. Hemothorax; 7. Pregnancy or lactation; 8. Active pulmonary infection; 9. Inability to tolerate medical thoracoscopy due to hemodynamic instability (blood pressure =90/60 mmHg) or severe hypoxemia (PaO2/FiO2 < 250); 10. Coagulation disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate of pneumothorax 12 months postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resorption of pneumothorax 8 weeks postoperatively;Time to air leak cessation;Time to chest tube removal;Recurrence rate of pneumothorax 2 years postoperatively;Recurrence rate of pneumothorax 5 years postoperatively;Patient satisfaction score;VAS scores within one week postoperatively;Complications associated with treatment regimens; | — |
Countries
China
Contacts
Public ContactKaige Wang
West China Hospital, Sichuan University,
Outcome results
None listed