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Observation on the callus formation induced by limb fracture combined with traumatic brain injury

Observation on the callus formation induced by limb fracture combined with traumatic brain injury

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600125014
Enrollment
Unknown
Registered
2026-05-20
Start date
2023-12-01
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fracture and Traumatic Brain injury

Interventions

Simple fracture of limbs group:None
Limb fracture combined with traumatic brain injury:None

Sponsors

The First Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Case group: 1. Age greater than 18 years old and less than 65 years old; 2. Patients with fractures in limbs combined with traumatic brain injury as determined by imaging examination. Control group: 1. Age greater than 18 years old and less than 65 years old; 2. Patients with simple fractures in limbs as determined by imaging examination.

Exclusion criteria

Exclusion criteria: Case group: 1. Patients who were admitted for treatment due to recent (less than 1 month) trauma combined with chronic severe infection or inflammation; 2. Patients with ischemic heart disease, severe cerebrovascular disease, liver or kidney diseases; 3. Patients who have recently (less than 1 month) used antibiotics or anti-inflammatory drugs; 4. Patients with incomplete clinical data. Control group: 1. Patients who were admitted for treatment due to recent (less than 1 month) trauma combined with chronic severe infection or inflammation; 2. Patients with ischemic heart disease, cerebrovascular disease, liver or kidney diseases; 3. Patients who have recently (less than 1 month) used antibiotics or anti-inflammatory drugs; 4. Patients with incomplete clinical data.

Design outcomes

Primary

MeasureTime frame
Bone density;Bone volume fraction;Bone surface area to tissue volume ratio;

Countries

China

Contacts

Public ContactMaosheng Xia

The First Hospital of China Medical University

xiamaosheng1981@163.com+86 24 8328 3360

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026