Aging
Conditions
Interventions
Treatment group:Administer cells at a fixed dose of 6×10^7 cells via infusion, once weekly for 3 consecutive doses.
Control Group:Administer via infusion at the same dose of placebo, once weekly, for a total of 3 consecutive doses.
Sponsors
Second Medical Center, Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 50 years; 2. Reduced intrinsic capacity or risk of decline; 3. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with severe diseases resulting from age-related changes in vital organs or with unstable disease status; 2. Patients with severe mental disorders or severe cognitive impairment; 3. Patients with physical disabilities; 4. Subjects deemed unsuitable for participation by the investigator due to potential non-compliance with the trial protocol or any other conditions that may affect their safety; 5. Patients who have previously received any form of stem cell-based therapy (including but not limited to autologous stem cells, allogeneic stem cells, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Biological age alterations derived from multimodal data models; | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement/Progression of Age-Related Baseline Conditions;Incidence of adverse events; | — |
Countries
China
Contacts
Public ContactWang Shuxia
Chinese PLA General Hospital
Outcome results
None listed