PBC-AIH overlap syndrome
Conditions
Interventions
Gold Standard:Liver tissue obtained by liver biopsy is assessed for the degree of fibrosis according to the Scheuer staging system after pathological staining.
Index test:Non-invasive diagnostic model based on routine laboratory indicators.
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Pathological examination confirmed PBC-AIH overlap syndrome; 2. There are data from transient elastography examination.
Exclusion criteria
Exclusion criteria: 1. Combined with other types of liver diseases, including viral, drug-induced, alcoholic, non-alcoholic fatty, genetic metabolic, and other autoimmune liver diseases; 2. Combined with severe cardiovascular and cerebrovascular diseases, hematologic diseases, or malignant tumors; 3. Combined with severe chronic lesions or functional failure of important organs such as the heart, lungs, or kidneys.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Routine laboratory indicators (fully automated biochemical analyzer indicators, blood cell analyzer indicators);Transient Elastography Index (Transient Elastography Index);Liver biopsy indicators (blood biochemical indicators, imaging indicators (liver stiffness values), pathological indicators (Scheuer staging)); | — |
Countries
China
Contacts
Public ContactJunli Zhang
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed