None
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Participants aged 18–28 years with a Beighton score >= 4/9 (diagnosed as Generalized Joint Hypermobility, GJH). A professional rehabilitation therapist will assess the participants using the Beighton scoring system; a score of >= 4 will be classified as generalized joint hypermobility. 2.They must have no major lower limb diseases and be able to complete the study procedures, voluntarily participating in the trial and signing an informed consent form. 3.All participants are required to have refrained from strenuous exercise for 24 hours prior to the experiment and must have no history of lower limb injury within the past six months. 4.Additionally, magnetic resonance imaging (MRI) will be used to further screen and exclude participants with other joint injuries.
Exclusion criteria
Exclusion criteria: 1. Patients with Marfan syndrome, EhlersDanlos syndrome, or cardiovascular disease who could not tolerate the study, and other patients with incomplete gait data;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Individualized ACL injury simulation probability; | — |
Secondary
| Measure | Time frame |
|---|---|
| Beighton score, Lower Limb Assessment Scale (LLAS);The "Spider" joint hypermobility questionnaire, and function-related scales.;Six-degree-of-freedom kinematic parameters of the knee joint during the early landing phase (e.g., 0–100 ms), including knee flexion angle, peak knee varus/valgus, and peak internal/external rotation.;Average ACL force / Mean ACL loading;Peak vertical ground reaction force (peak vGRF), time from initial contact to peak vGRF, average loading rate, time to stabilization (TTS), total path length of the center of pressure (COP) trajectory;Mean and peak %MVC of key muscle groups during the pre-landing pre-activation phase and the 0–100 ms post-landing period, activation onset time, time to peak activation, and intermuscular correlation-; | — |
Countries
China
Contacts
Kunshan Rehabilitation Hospital