Cancer-related cognitive impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Female, 18-65 years old 2.Pathologically or clinically confirmed diagnosis of breast cancer, clinical stage I-IIIa 3.Plan to receive chemotherapy (either neoadjuvant or adjuvant chemotherapy) 4.Able to understand and complete cognitive and EEG assessments 5.Voluntarily participate in the study and sign the informed consent form
Exclusion criteria
Exclusion criteria: 1.Past or current clear central nervous system disease 2.Severe mental disorder or cognitive impairment, impact assessment completed 3.Combined with severe cardiopulmonary disease, not suitable for moderate-intensity exercise 4.Patients using drugs that may affect cognition, mood and sleep 5.Refusing to participate or lacking necessary clinical or pathological data 6.Other circumstances that the researcher believes are not suitable for participating in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Trail making test-b; | — |
Secondary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment Scale, MoCA;Electroencephalogram examination;Functional Assessment of Cancer patients-Cognitive function scale, FACT-Cog;Hospital Anxiety and Depression Scale, HADS;Multidimensional fatigue assessment scale, MFI-20; | — |
Countries
China
Contacts
The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial Hospital)