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A study on the perioperative rapid rehabilitation of patients undergoing off-pump coronary artery bypass grafting with liposomal bupivacaine stellate ganglion block

A study on the perioperative rapid rehabilitation of patients undergoing off-pump coronary artery bypass grafting with liposomal bupivacaine stellate ganglion block

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600124968
Enrollment
Unknown
Registered
2026-05-19
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Bypass Grafting

Interventions

Liposomal bupivacaine LSGB group (Group L):Group L was injected with 0.665% bupivacaine liposomes
Ropivacaine LSGB group (Group R):Group R was injected with 0.25% ropivacaine

Sponsors

The First Affiliated Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Surgical type: Elective coronary artery bypass grafting (without stopping); 2. Age: 45-75 years old, gender not limited; 3. New York College of Cardiology (NYHA) cardiac function classification II or III, left ventricular ejection fraction (LVEF) > 50%; 4. Be capable of mastering the research procedures and the application of various scales, possess the ability to communicate efficiently with follow-up personnel, clearly understand the specific contents of the informed consent form, and make a commitment to voluntarily participate in the research. Both patients and their families voluntarily sign the informed consent document

Exclusion criteria

Exclusion criteria: 1. Refuse to participate; 2. Local anesthetics, coagulant function abnormality, infection, wound puncture in immune function inhibition; 3. Serious psychological disorders can't cooperate with SGB, neck dissection is unusual, stellate ganglion block failure.

Design outcomes

Primary

MeasureTime frame
Postoperative analgesia score;

Secondary

MeasureTime frame
sleep quality;Anxiety tendency;Postoperative recovery status;Perioperative hemodynamic indicators and myocardial marker indicators;Perioperative myocardial marker indicators;

Countries

China

Contacts

Public ContactYu Chen

The First Affiliated Hospital of Nanjing Medical University

chenyu_njmu@126.com+86 25 8371 4511

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 21, 2026