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Risk Prediction of Hypotension after Spinal Anesthesia Using Preoperative Frailty Assessment in Elderly Cerebrovascular Disease Patients

Association Between Preoperative Frailty and Spinal Anesthesia-Induced Hypotension in Elderly Non-Cardiac Surgery Patients with Cerebrovascular Disease: A Risk Prediction Study

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600124957
Enrollment
Unknown
Registered
2026-05-19
Start date
2026-05-25
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension

Interventions

Sponsors

Tianjin Beichen Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 65 years; 2.Definite diagnosis of cerebrovascular disease; 3.Scheduled to undergo elective or urgent surgery under spinal anesthesia; 4.American Society of Anesthesiologists (ASA) physical status classification I-III; 5.Signed written informed consent by the patient or legal guardian;

Exclusion criteria

Exclusion criteria: 1.Emergency surgery; 2.Presence of severe hypotension or uncontrolled hypertension prior to surgery; 3.Presence of severe cardiac disease, severe hepatic insufficiency, or end-stage renal disease; 4.Conditions that may interfere with accurate upper limb blood pressure measurement; 5.Conditions that may affect the assessment of frailty; 6.Failure to provide signed written informed consent.

Design outcomes

Primary

MeasureTime frame
The incidence of hypotension in the two groups;

Secondary

MeasureTime frame
New or Worsened Postoperative Neurological Deficits;Use of Vasoactive Agents;Unplanned ICU admission rate;Intraoperative Blood Pressure Variability;Postoperative length of hospital stay;30-day readmission rate;Imaging-confirmed new-onset cerebral infarction or cerebral ischemia during the perioperative period;Incidence of postoperative delirium;

Countries

China

Contacts

Public ContactChao Qi

Tianjin Beichen Hospital

416210213@qq.com+86 22 26836315

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026