Skip to content

Construction of a Risk-Stratified Personalized Bowel Preparation Regimen for Colonoscopy Under General Anesthesia Based on a Predictive Model for Bowel Preparation Failure and Evaluation of Its Effectiveness

Construction of a Risk-Stratified Personalized Bowel Preparation Regimen for Colonoscopy Under General Anesthesia Based on a Predictive Model for Bowel Preparation Failure and Evaluation of Its Effectiveness

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600124953
Enrollment
Unknown
Registered
2026-05-19
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal diseases

Interventions

Control group:All patients received standardized paper and video education and a unified 3L compound polyethylene glycol electrolyte powder in divided doses. On this basis, they received three preset
Intervention group:On the same basis of the control group, the nurse-led dynamic closed-loop precise navigation nursing model based on wechat platform was implemented. An exclusive wechat group (patie
Type 3 to 5 push standardized recommendations (such as adding warm water and a

Sponsors

Guangdong Women and Children Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Have indications for colonoscopy and no contraindications; 2. Aged 18–65 years; 3. Classified as high-risk population with a risk stratification assessment score >0.5 by the predictive model of this study; 4. Proficient in using WeChat and able to provide feedback accordingly; 5. Voluntarily participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Pregnant or breastfeeding women; 2. Those allergic to bowel cleansing agents or anesthetic drugs; 3. Those who have undergone abdominal surgery or abdominal radiotherapy within the past 3 months; 4. History of colorectal resection (excluding appendix or hemorrhoid surgery); 5. Presence of gastrointestinal obstruction, perforation, or bleeding, or diagnosis of digestive system tumors or inflammatory bowel disease; 6. Those with severe liver, kidney, or cardiac dysfunction, active malignant tumors, or severe hematological disorders; 7. Those with severe cognitive impairment, mental illness, or language communication difficulties that prevent compliance with assessment; 8. Diminished swallowing reflex; 9. Missing key clinical data that may affect risk stratification assessment; 10. Previous use of laxatives for bowel preparation; 11. Uncontrolled hypertension (systolic blood pressure >170 mmHg or diastolic blood pressure >100 mmHg); 12. Hypoglycemia (blood glucose 13.9 mmol/L); 13. Electrolyte imbalance or dehydration; 14. Women who are menstruating; 15. Those who refuse to participate in this study.

Design outcomes

Primary

MeasureTime frame
Bowel preparation adequacy rate;Boston Bowel Preparation Scale (BBPS) scores by segment and total score;

Secondary

MeasureTime frame
Colonoscopy procedure time;Adenoma detection rate;Patient adherence;Patient tolerability;Patient acceptability;

Countries

China

Contacts

Public ContactGuo Jingjing

Guangdong Women and Children Hospital

421432199@qq.com+86 20 3915 1810

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 30, 2026