vitiligo
Conditions
Sponsors
The Fifth People's of Hainan Province
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Age 18–60 years. 2.Clinical diagnosis of non-segmental vitiligo. 3.Progressive group: VIDA score = +1; Stable group: VIDA score = 0 for =6 months. 4.Healthy controls: matched for age/sex, no autoimmune/endocrine/significant skin disease. 5.Willing to provide written informed consent and comply with study procedures.
Exclusion criteria
Exclusion criteria: 1.Use of systemic corticosteroids/immunosuppressants in past 3 months. 2.Known endocrine disorders affecting HPA axis. 3.Major psychiatric disorders or medications affecting HPA axis. 4.Hair dyeing/chemical treatment in past 3 months. 5.Pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HCC (Hair Cortisol Concentration);Serum cortisol;Adrenocorticotropic Hormone;Corticotropin-Releasing Hormone Receptor;Microphthalmia-Associated Transcription Factor; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tyrosinase; | — |
Countries
China
Contacts
Public ContactDanping Pan
The Fifth People's of Hainan Province
Outcome results
None listed