Psoriasis
Conditions
Interventions
control group:None
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=18 years, regardless of gender; 2. Signed the informed consent form; 3. Clinical diagnosis of plaque psoriasis. 4. Body Mass Index (BMI) categorized as overweight or obese. 5. For female patients: No plans for pregnancy or oocyte donation during the study period and voluntary use of highly effective physical contraception.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women. 2. Individuals deemed by the investigator to be unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients undergoing weight loss treatment who achieve a Psoriasis Area and Severity Index (PASI) score below 3; | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of patients undergoing weight loss treatment who achieve a Dermatology Life Quality Index (DLQI) score below 6 at Week 12 and Week 24.;Changes from baseline in body weight at Week 12 and Week 24 in patients undergoing weight loss treatment;Proportion of patients undergoing weight loss treatment who achieve a Physician’s Global Assessment (PGA) score of 0 or 1 at Week 12 and Week 24.;Proportion of patients undergoing weight loss treatment who achieve a PASI score below 3 at Week 12;Changes from baseline in Body Mass Index (BMI) at Week 12 and Week 24 in patients undergoing weight loss treatment;Changes from baseline in waist circumference at Week 12 and Week 24 in patients undergoing weight loss treatment;Changes from baseline in waist circumference, and waist-to-hip ratio at Week 12 and Week 24 in patients undergoing weight loss treatment; | — |
Countries
China
Contacts
Public ContactGuo Jinzhu
Peking University Third Hospital
Outcome results
None listed