None
Conditions
Interventions
Alfentanil Sequential Dose Group:Induction regimen: All pediatric patients received propofol 2.5 mg/kg (administered within 30 seconds).
Study drug administration: Administered 1 minute prior to propo
if insertion failed, the dose was increased for the next patient.
Sponsors
The Zhongshan Ophthalmic Center,Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
7 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Age 7 to 12 years old; 2. Undergoing elective day surgery; 3. ASA physical status I-II; 4. Body Mass Index (BMI) between 14 and 24 kg/m²; 5. Accompanied by a fully capable guardian within 24 hours after discharge.
Exclusion criteria
Exclusion criteria: 1. Allergy to opioids; 2. Unresolved upper respiratory tract infection within the past 1 week; 3. Abnormal heart, lung, liver, or kidney function, or metabolic diseases; 4. Airway anatomical abnormalities (e.g., micrognathia, laryngomalacia, macroglossia) or OSAHS (Obstructive Sleep Apnea-Hypopnea Syndrome); 5. Use of analgesics, sedatives, or other psychotropic drugs within the past 2 weeks; 6. Children with any other conditions deemed unsuitable for enrollment by the investigator; 7. Refusal to sign the informed consent form;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success of LMA insertion;ED50 and ED95; | — |
Secondary
| Measure | Time frame |
|---|---|
| Placement operation time;Hemodynamic indicators; | — |
Countries
China
Contacts
Public ContactRui Zhang
The Zhongshan Ophthalmic Center,Sun Yat-sen University
Outcome results
None listed