Idiopathic Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.The diagnosis of pulmonary arterial hypertension was confirmed through right heart catheterization, and the diagnosis met the criteria of the first category (pulmonary arterial hypertension of arterial origin) or the fourth category (pulmonary arterial hypertension caused by chronic thromboembolic pulmonary hypertension and/or other obstructive lesions of the pulmonary arteries) in the "2022 ESC/ERS Guidelines for the Diagnosis and Treatment of Pulmonary Arterial Hypertension". 2.The first category includes patients who have undergone targeted drug therapy for three months, and the fourth category includes patients who have received six or more pulmonary artery balloon angioplasties or have reached the treatment endpoint. 3.WHO functional grade I or II or IIIpatients; 4.>=18 years old; 5.Sign informed consent;
Exclusion criteria
Exclusion criteria: 1.The patient's compliance was poor and the test could not be completed as required; 2.Unable to carry out pulmonary rehabilitation exercise due to disability, congenital malformation and other reasons; 3.The cardiopulmonary exercise test cannot be completed after assessment. 4.The expected survival rate is less than or equal to one year.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Six-minute walking distance;The number of acute heart failure exacerbations within one year for the patient; | — |
Secondary
| Measure | Time frame |
|---|---|
| Health Status Survey Questionnaire;The hospitalization expenses incurred due to acute exacerbation during the course of one year;Generalized anxiety disorder, Patient Health Questionnaire-9 Score;N-terminal pro-brain natriuretic peptide, albumin, hemoglobin indicators; | — |
Countries
China
Contacts
Beijing Chao-Yang Hospital, Capital Medical University